Except for female gender, total PBC-40 score correlated significantly with longer disease duration (r = 0.171, P = 0.001), presence of cirrhosis (r = 0.121, P = 0.02), the detection of anti-sp100 (r = 0.123, P = 0.02), living in urban areas (r = 0.133, P = 0.01) and unemployment (r =-0.161, P = 0.008). Here, SP100 is linked to Cirrhosis.