Although STEAP1 has no iron-reducing function (Ohgami et al., 2005), STEAP1 expression in Ewing tumors correlates favorably with cellular reactive oxygen species, which stimulates the production of oxidative stress-sensitive and invasive genes, which is consistent with earlier research: Thyroid epithelial cell proliferation is aided by increased STEAP1 expression (Pan et al., 2008). The gene discussed is STEAP1; the disease is Ewing sarcoma.