An experimental study on AML cells showed that DHA-induced autophagy in AML cells affected the AMPK/mTOR/p70S6k signaling pathway, degraded ferritin, increased the intracellular unstable iron pool, accumulated large amounts of ROS, induced lipid peroxidation, and ultimately led to ferroptosis (Du et al., 2019). This evidence concerns the gene MTOR and acute myeloid leukemia.