RPS6KB1 and acute myeloid leukemia: An experimental study on AML cells showed that DHA-induced autophagy in AML cells affected the AMPK/mTOR/p70S6k signaling pathway, degraded ferritin, increased the intracellular unstable iron pool, accumulated large amounts of ROS, induced lipid peroxidation, and ultimately led to ferroptosis (Du et al., 2019).