In addition to the cancer pathways identified, the 24 genes were mapped to the following signaling pathways, namely PI3K-Akt, Wnt, P53, Notch, and NF - Kappa B signaling pathway which were shown to be the critical pathways (Hellmark and Segelmark, 2014; Xie et al., 2019). Here, TP53 is linked to cancer.