Compared to MC group, IL-6 protein levels (0.5713 ± 0.0941 vs. 0.9316 ± 0.0808, p < 0.05), p-STAT3/STAT3 protein ratio (0.6727 ± 0.0567 vs. 0.9943 ± 0.1119, p < 0.01) and p-p65/p65 ratio (0.6074 ± 0.0881 vs. 0.8420 ± 0.0753, p < 0.05) in MD group decreased significantly (Figure 1F). The gene discussed is STAT3; the disease is Menkes disease.