In addition, we found four proteins with 50 crotonylation sites, myosin 1b, ribosomal protein S11, LONP1, and cytochrome P450 family 11 subfamily A member 1, which showed more than 2.5‐fold down‐regulation of crotonylation levels, suggesting a potential function in the development of PCOS. The gene discussed is RPS11; the disease is polycystic ovary syndrome.