In the shMND1 + shTKT group, tumor volume was the smallest, the expressions of ki67, MND1, N-cadherin, and Vimentin were the lowest, and the expression of E-cadherin was the highest (Fig. 8 M–N). These results demonstrated that TKT was involved in regulating the proliferation, invasion, migration, and glycolytic metabolism of GC cells. The gene discussed is CDH2; the disease is neoplasm.