LPAR2 and Abnormal intestine morphology: On the other hand, it is noteworthy that the reduction in histological damage caused by DBIBB was comparable in normal and NOD/SCID mice, and the correlation between apoptosis and histological damage was weak in WT and Lpar2−/− mice, which indicate that inhibition of epithelial apoptosis is likely to be one, but not the only factor that contributes to the protective effect of LPAR2 against IND-induced enteropathy.