tool to screen for GUCA2A and COL3A1 expression in multiple cancer types and found that GUCA2A was significantly downregulated in 11 cancer type (Fig. 4A) and COL3A1 was significantly upregulated in 18 cancer type (Fig. 4B), especially in colon and rectal adenocarcinoma. The gene discussed is COL3A1; the disease is cancer.