PPARA and systemic lupus erythematosus: Downregulated DEGs were particularly enriched in mineral absorption, fat digestion and absorption, PPAR signaling pathway, Pancreatic secretion and Nitrogen metabolism, whilst the Cell cycle, Spliceosome, RNA transport, DNA replication and Systemic lupus erythematosus were identified as the most represented pathways for the upregulated DEGs (Supplementary Fig. S3, Table 6).