CREB5 and colorectal carcinoma: By confirming the binding of miR-3913-5p to the CREB5 3′UTR and ATF2 interacting with the promoter of miR-3913-5p, the ATF2/miR-3913-5p/CREB5 axis was identified to play a vital role in CRC development, suggesting that it might serve as potential targets for managing CRC.