We found that ATF2 endogenous protein were co-immunoprecipitated using an anti-CREB5 antibody, while anti-ATF2 antibody could co-immunoprecipitate CREB5 from LoVo and SW480 cell extracts, indicating that CREB5 and ATF2 interact with each other in CRC cells (Fig. 5c). Here, ATF2 is linked to colorectal carcinoma.