STXBP5 and schizophrenia: Based on existing research, the host gene of hsa_circ_0005035 (i.e., IGF1R) has been observed to play an important role in the pathogenesis of schizophrenia, and STXBP5 (i.e., the host gene of hsa_circ_0007762) were involved in the docking and fusion of synaptic vesicles and presynaptic membranes.