Other researchers found that the IL-17 family member IL-17D can inhibit tumor progression by recruiting natural killer cells to mediate tumor rejection.310 Moreover, lymphocytes can induce tumor cell death and proliferation by activating the p53 signaling pathway and secreting IL-17.311 Furthermore, although IL-17 promotes the formation of blood vessels in the tumor microenvironment to facilitate nutritional access by tumor cells for their growth and development, this vascular network also provides a direct pathway for antitumor immune cells to enter the tumor interior. This evidence concerns the gene IL17A and neoplasm.