SMAD4 and lung cancer: The ability of IL-17 to recruit dendritic cells contributes to antitumor immunity in the B16 melanoma312 and Pten/Smad4 deficient lung cancer models.313 Furthermore, the molecular fingerprints of Pten/Smad4 deficient lung cancer cells314 differ from those of KrasG12D lung cancer cells,315 suggesting that IL-17 functions differently in these two tumor models.