Transwell results shown in Figure 6G–6I and Figure 6A–6C combined with wound healing assay results shown in Figure 6J, 6K and Figure 6D, 6E both suggested that UCHL1 silencing significantly reduced tumor cell migration and invasion capabilities, while concomitant treatment with PKM2 overexpression vector completely reversed such effects. This evidence concerns the gene UCHL1 and neoplasm.