GSVA showed that the remarkable enrichment pathways in ERGcluster A included “primary bile acid biosynthesis”, “tryptophan metabolism”, “maturity onset diabetes of the young”, etc. The remarkable enrichment pathways in ERGcluster B contained “basal transcription factors”, “p53 signaling pathway”, “cell cycle”, “focal adhesion”, “pathways in cancer”, and “pancreatic cancer”, and these enrichment pathways may be associated with the poorer prognosis in ERGcluster B (Figure 3E). The gene discussed is TP53; the disease is familial pancreatic carcinoma.