In the tumor associated stroma, the proportion of DAB2+ (fold change 4.64, p = 0.029), CD68+ (fold change 2.04, p = 0.02) and DAB2+ CD68+ (fold change 3.15, p = 0.028) was significantly increased in metastatic compared to matched primary tumors (Fig. 8H). The gene discussed is DAB2; the disease is neoplasm.