TGFB1 and colitis: p40N120 recombinant peptide (28–120 aa) containing the first two alpha helices showed the same or higher regulatory effects on epigenetic imprint on Tgfb1 in intestinal epithelial cells, leading to sustained protection against colitis compared to the full-length p40 (p40F) and p40N180 peptide (28–180 aa) with the first three alpha helices.