WNT5A and Nephroblastoma: The finding that some podocyte-associated genes including WNT5A are specifically upregulated in SIX1/2-Q177R blastemal tumors, and that the canonical podocyte lineage-specific markers MAFB and PODXL colocalize with SIX1 and WNT5A in Wilms tumor tissue is intriguing when considered within the framework of the NPC differentiation continuum.