Almost all characteristics were evenly distributed between the two groups, including age, gender, Child‐Pugh score, albumin‐bilirubin index, etiology, HBV‐DNA index, alpha‐fetoprotein (AFP) level, number of RFA treatments, family history of HBV, smoking history, drinking history, platelet count, prothrombin time, number of tumors, and tumor size. Here, F2 is linked to neoplasm.