Assignment: BMI (abnormal = 1, normal = 0); Smoking (yes = 1, no = 0); Anxiety (yes = 1, no = 0); HP infection (yes = 1, no = 0); Family history of gastrointestinal tumor (yes = 1, no = 0); Combination with chronic gastric disease (yes = 1, no = 0); CASP3 rs12108497 locus (TC/CC type = 1, TT type = 0); Rs1862610 locus of ITGA1 gene (AC/AA type = 1, CC type = 0); GSTM1 gene (blank type = 1, WT = 0). The gene discussed is ITGA1; the disease is digestive system neoplasm.