TSLP and asthma: Second, the asthma-associated SNP rs1837253 in the TSLP locus has a higher odds ratio in the top quartile of SRD (sense organs, respiratory, dermatologic) topic weight (1.17 ± 0.02) than in the bottom quartile (1.05 ± 0.02; P = 6 × 10−6 for interaction test (FDR = 0.004 < 0.1); P = 1 × 10-3 for top/bottom quartile test (FDR = 0.08 < 0.1)).