CD8A and infection: To examine the potential role of the malate shuttle in antiviral CD8+ T cell responses, we monitored the expression of malate shuttle-associated genes in CD8+ T cells collected from mice infected with lymphocytic choriomeningitis virus (LCMV) Armstrong, which induces transient infection and acute CD8+ T cell responses, or LCMV clone 13 strain, which induces persistent infection and chronic CD8+ T cell responses9.