The expression of Cd34 and the numbers of CD34+ cells were increased in the livers of CflarLKO mice fed the CDE diet and wild-type mice fed the CDAHFD diet (Supplementary Fig. 9d–i), suggesting that the expansion of CD34+ cells is not specific to Fgf18 Tg mice but a more generalized phenomenon in liver fibrosis. Here, CD34 is linked to Hepatic fibrosis.