Intriguingly, the expression of Fgf18 was also elevated in choline-deficient, L-amino acid-defined, high-fat diet (CDAHFD)-induced murine MASH or 3,5-diethoxycarbonyl-1,4-dihydrocollidine–supplemented (DDC) diet-induced liver fibrosis models in wild-type mice33,34 (Supplementary Fig. 4a–h). This evidence concerns the gene FGF18 and Hepatic fibrosis.