Notably, although an antifibrotic effect of IFN‐γ has been reported in renal fibrosis experimental models (Oldroyd et al., 1999; Poosti et al., 2015), both TH1 and TH2 cells have previously been shown to facilitate the profibrotic process in the UUO model (Liu et al., 2012; Tapmeier et al., 2010). Here, IFNG is linked to renal fibrosis.