Likewise, a robust decrease in the expression of CD338 (ABCG2), an ATP-binding cassette transporter, was also noted in 22RV1 shMALAT1 cells compared with 22RV1-shSCRM (Fig. 2I), suggesting that MALAT1 modulates stemness in prostate cancer cells. This evidence concerns the gene MALAT1 and prostate carcinoma.