ERVW-1 and HIV infectious disease: Generally, a modest effect of HIV infection was observed in these cells of monocytic origin, with the increased expression of HERV-W in primary monocyte-derived macrophages soon after their exposure to HIV, while a decreased expression of HERV-K (HML-6) is present at 36 hours after HIV infection in macrophages derived from healthy donors which does not persist at 6 days.