Indeed, a study on the major histocompatibility complex type I inhibitory molecule, immunoglobulin‐like transcript 4, has shown a higher affinity for the HLA‐B*35:03 from the Px group than for the HLA‐B*35:01 (PY group), which could in turn impact on disease progression differently in the context of HIV infection.18 The gene discussed is HLA-B; the disease is HIV infectious disease.