Several identified lncRNAs play crucial roles in neuron function and maintenance in neurodegenerative diseases, such as Tug1, participating in normal photoreceptor development and contributing to rod differentiation and survival (Carrella et al., 2020), and Meg3, regulating the process of light-induced retinal damage (Zhu et al., 2018). Here, MEG3 is linked to neurodegenerative disease.