MYC and lymphoma: We previously demonstrated that CJL disrupts locomotor activity rhythms in c57BL/6J mice and alters rhythmic gene expression patterns in peripheral tissues of both healthy and tumor-bearing mice.11 To examine the impact of CJL on peripheral clocks in the context of MYC-driven lymphoma, we euthanized Eμ-MYC mice at ZT9, whenBmal1 mRNA is typically low and REV-ERBα protein is typically high in peripheral organs.