Eμ-MYC mice can develop tumors with biological similarities to Burkitt lymphoma or diffuse large B cell lymphoma that exhibit divergent activation of c-MYC.48 This is consistent with our observations of variable levels of c-MYC protein in the liver (Figure 4A) and spleen (Figure 4D) of the Eμ-MYC mice independent of lighting condition. Here, MYC is linked to diffuse large B-cell lymphoma.