The mean age of the total population was 60.1 years old (range 32-77 years),62 patients (68.89%) were ≤65 years old, 55 patients (61.11%) were male, 75 patients (83.33%) were adenocarcinoma and 40 cases had gene mutation (31 were EGFR+,7 were ALK+, and 2 were ROS1+), 73(81.11%) patients with KPS ≥70. The gene discussed is ROS1; the disease is adenocarcinoma.