Similarly, the level of IL-2R, Oncostatin M (OSM), IL-6, IL-8, IL-9, IL-10, IL-17a, IL-22, and soluble CD30 is decreased in either pediatric or adult ALK+ ALCL patient samples after they reached complete remission (114–116). This evidence concerns the gene TNFRSF8 and anaplastic large cell lymphoma.