ALK and anaplastic large cell lymphoma: Based on the recent understanding of the genetic basis of ALK- ALCL and those that occur in breast-implant ALCL, the updated 5th edition of the World Health Organization Classification of Haematolymphoid Tumours (5), and the International Consensus Classification (ICC) of Mature Lymphoid Neoplasms (7) recognize three subtypes, namely ALK+ ALCL, ALK- ALCL, breast implant-associated ALCL (BI-ALCL) (5).