High levels of Nrf2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulationThe role of Nrf2 in migration and invasion of human glioma cell U251The E3 ubiquitin ligase NEDD4-1 mediates temozolomide-resistant glioblastoma through PTEN attenuation and redox imbalance in Nrf2-HO-1axis. This evidence concerns the gene NEDD4 and central nervous system cancer.