PTBP1 and neoplasm: The results showed that ASEs up-regulated in BLCA with high-level neoplasm grade were enriched to several RBPs’ motifs, including “poly-T” motifs and polypyrimidine tract (Py-tract) sequence of HuR, CPEB4, TIA1, HNRNPC, PTBP1, RALY and ZC3H14, and motifs of PCBP2 and SNRNP70 (Figures 6A, B).