Serum albumin. Hypoalbuminemia upon hospital admission, possibly in the context of changes in vascular permeability leading to a greater capillary leakage of albumin (60), among other factors, such as the underlying nutritional status, nitrogen balance, or renal replacement therapy (61,62), has been associated with poor outcomes in patients COVID-19 (63-65). The gene discussed is ALB; the disease is COVID-19.