ENO1 and neoplasm: ENO1 can increase the process of glycolysis, help prevent immune cell destruction and the role of growth inhibitors in tumors (Hsiao et al., 2013), promote the growth of tumor blood vessels, provide more nutrients to cells, promote tumor growth and migration (Huang et al., 2022a), promote malignant proliferation, and act on tumor-related pathways (Hua et al., 2021).