During the assays, it was observed that the survival, migration, invasion, and proliferation of cells in the knockdown group were substantially poorer than that of the negative control group (NC; Figs. 3C–3H), verifying that the expression of NMRAL2P improves the viability, migration, invasion, and proliferation of head and neck tumor cells. The gene discussed is NMRAL2P; the disease is head and neck neoplasm.