The post hoc analysis showed that PAI-1 levels weresignificantly higher in the Alzheimer group (23% more) as comparedto amnestic mild cognitive impairment (p < 0.001;95% CI: −2.02, −0.71) and controls (36% more) (p < 0.001; 95% CI: −3.27, −1.19). Here, SERPINE1 is linked to Cognitive impairment.