3q rearrangements are rare in ALL and an association of high EVI1 expression with cytogenetic subgroups was not found, but elevated levels of EVI1 were again linked with poor prognosis in patients and enhanced cell survival, increased growth, and elevated leukemia initiation capacity in an experimental setting.41,42{Stevens, 2014 #151}. Here, RUNX1 is linked to acute lymphoblastic leukemia.