IL6 and Orofacial dyskinesia: However, in two studies (Peroza et al., 2016; Sonego et al., 2021) co-treatment with antioxidants (isoflavones, cannabidiol) did not reduce IL-6 levels and in two studies (Peroza et al., 2016; Sonego et al., 2018) striatal IL-6 levels did not correlate with the frequency of orofacial dyskinesia.