Specifically, we identified LYVE1 as a target gene of miR-492, and its downregulation caused by miR-492 overexpression in HCC cells was partially offset by circ_0129047 overexpression (Figure 5), demonstrating the involvement of the circ_0129047/ miR-492/ LYVE1 axis in HCC. The gene discussed is LYVE1; the disease is hepatocellular carcinoma.