In comparison to individuals without PAD, PAD patients demonstrated lower mean [SD] plasma concentrations of HGF (0.20 [0.05] vs 0.33 [0.23] ug/mL, p = 0.011], BMP-9 (0.13 [0.17] vs 0.18 [0.02] ug/mL, p = 0.022), endoglin (1.32 [0.23] vs 1.54 [0.16] ug/mL, p = 0.01), follistatin (0.52 [0.32] vs. 0.76 [0.38] ug/mL, p = 0.003), HB-EGF (0.02 [0.01] vs 0.05 [0.04] ug/mL, p = 0.044), and PLGF (3.01 [3.17] vs. 5.04 [2.92] pg/mL, p = 0.002). Here, ENG is linked to peripheral arterial disease.