Breast cancer environment was reached in higher numbers of Phylum Proteobacteria, families Micrococcaceae, Caulobacteraceae, Rhodobacteraceae, Nocordioidaceae, and Methylobacteriaceae, and genus Propionicimonas compared to benign healthy breast tissue, even with different types of breast cancer like HER2, Luminal A, Luminal B, ER+ the type of microbiome was diverse and different [154]. Here, ESR1 is linked to breast cancer.