Importantly, the epidermal basal cells in cluster 8 of KO samples were also enriched with the expression of inflammatory cytokines and chemokines, including Tslp, Il1f9 (IL-36γ), and Cxcl16 (Figure 4E), all of which have been demonstrated to contribute to the pathogenesis of psoriasis (63–65). Here, TSLP is linked to psoriasis.