The gene activity of CDH5 in different tumors and relative normal tissues were first assess and the results indicated that the activity of CDH5 was lower in tumors including BLCA, BRCA, CESC, COAD, KICH, KIRP, LUAD, LUSC, PRAD, READ, and UCEC but it was higher in tumors including GBM, KIRC, LIHC, and THCA (Figure 3A). The gene discussed is CDH5; the disease is glioblastoma.