Among the identified fibroblast subsets, a notable increase in the proportion of mesenchymal fibroblasts was observed in keloids compared to regular scars, along with a consistent upregulation of genes related to ECM formation, such as collagen type I alpha 1/2 (COL1A1/2), periostin (POSTN) and fibronectin 1 (FN1). Here, FN1 is linked to keloid.