We elevated A3G expression was significantly associated with unfavorable prognosis as well as clinical pathology of glioma through the utilization of the TCGA-GBMLGG and CGGA dataset (Supplementary Figures 11A–F) and confirmed a correlation between the expression of A3G and A3C (Supplementary Figures 11G, H). This evidence concerns the gene APOBEC3G and central nervous system cancer.