,115 By comparing the RNA splice, poly(A) tail length, and m6A modifications of B cells between the control and Prmt5 KO groups, it was found that the levels of CCL22 and IL-12a expressed by TIB cells in tumor tissues were higher than those in the control group; these differences likely played an important role in attracting T cells and antitumor activity. The gene discussed is PRMT5; the disease is neoplasm.