26 transcription factors were represented in all groups, and included those implicated in diseases such as cancer (MYC, TP53, YAP1, RBL2, E2F7, BRD4, MXl1), inflammation (CEBPB, BHLHE40), oxidative stress (NFE2L2), and neurological conditions (NEUROG2, SUMO2). The gene discussed is SUMO2; the disease is cancer.