DYNC2H1 and Jeune syndrome: Mutations in human DYNC2H1, the heavy chain subunit of dynein-2, are associated with Asphyxiating Thoracic Dystrophy (ATD) and Short-rib Polydactyly Syndrome (SRP) Type III (Dagoneau et al., 2009; Merrill et al., 2009), conditions that are consistent with ciliary dysfunction.