This study is comparable to that of Wang et al. [30], who found that the CD4+ T helper subset may play a prominent role in OLP immunopathology and demonstrated that tissue inflammation is orchestrated by proinflammatory cytokines (IL-6, IL-1, and TNF) and chemokines via CD4 (Th17) that attract and activate Th1 cells. Here, TNF is linked to oral lichen planus.