Interleukin 6 (IL-6) isa pro inflammatory cytokine, the presence of IL-6 is normal in tissues with normal conditions whereas, in abnormal conditions it leadsto inflammation due to irregular production and over exposure, in-case of Type 2 Diabetes Millets (T2DM) it leads to resistance towardsinsulin. This evidence concerns the gene IL6 and type 2 diabetes mellitus.