SETD2 and breast carcinoma: Recent studies have successfully established the correlation between HIF-1 α and microRNAexpression in the hypoxic condition in colon and breast carcinoma cell lines[14].Hypoxiccondition induces the upregulation of miRNA210 in human placental choriocarcinoma JAR cell lines [15].Among the hypoxia-regulated micro RNAs, miR210 is widely studied for its involvement in pathological conditions.