VEGFA and HELLP syndrome: Further, depletion of vascular endothelialgrowth factor (VEGF) in the podocytes makes the endotheliosis a more efficient factor to block the slit diaphragms in the basementmembrane, leading to decreased glomerular filtration and proteinuria VEGF and its receptors expressions are highly dis regulated insevere preeclampsia and HELLP syndrome [5].