miR-210 is involved in the regulation ofhepatocellular carcinoma via HIF-1α and HIF-3α[17].Again, miR-210 is a target ofHIF-1 and HIF-2 and is closely correlated with the prognosis of patients with renal cancer [18].Collectively, these studies support that hypoxia, potentially through induction of HIF-1α, up-regulates miR-210 expression. This evidence concerns the gene HIF1A and carcinoma.