The study suggested that beclin 1 (core protein in autophagosome nucleation) and ATG (AuTophaGy-related gene) gene complex triggers PMC203-induced autophagy to lower the TB burden on macrophage cell lines, thereby suggesting its potential to use as an anti-TB drug candidate for treating both antibiotic-sensitive and resistant TB (Rahim et al., 2022). This evidence concerns the gene BECN1 and tuberculosis.